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Symposium on the Evolution of Biomolecular Structure

Table of Contents

Talks - Friday, June 4

Morning Session Page
In Vitro Selection and Screening of Novel RNA Polymerases by Andrew Ellington 1
Evolutionary Rules Specifying Protein Folding and Function by Rama Ranganathan 2
"Wide Open" 1.3 A Structure of the Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Targetby Ladislau Kovari 3
Hyperthermophilic Proteins Rock by Claire Vieille 4
 
Afternoon Session
Addressing Resistance in Antimicrobial Design by Margaret Riley 5
AScale-free Evolution: From Proteins to Organisms by Nikolay Dokholyan 6
Directed Evolution of Human Estrogen Receptors for Fun and Profit by Huimin Zhao 7
The Evolution of Genetic Organization in Digital Organisms by Charles Ofria 8

Posters - Ballroom, University Club

1. Optimizing Hydrogen-bond Networks in Protein-ligand Interfaces by Arora, Sameer 9
2. Effects of Donors and Acceptors on the Energetics and mechanism of Proton, Hydrogen and Hydride Release from Imidazole by Bu, Yuxiang and Cukier, Robert 10
3. Simulating Nucleic Acids: Towards Implicit and Hybrid Solvation Models by Chocholoušová, Jana 11
4. Directed Evolution of Soluble Single-chain Human Class II MHC Molecules by Esteban, Olga and Zhao, Huimin 12
5. Comparison of Implicit and Explicit Solvation for Modeling of Biological Macromolecules in Aqueous Solution by Michael Feig 13
6. Effect of Sequence Length and Number of Taxa on Phylogeny Reconstruction with Natural Selection by Hang, Dehua 14
7. Empirical Scoring Functions in Structure-based Molecular Screening and Dockingby He, Litian 15
8. Structure/Function Analysis of the Bacillus subtilis Sporulation-specific Transcription Factor SpoIIID by Himes, Paul 16
9. Molecular Dynamic Simulation of Escherichia coli Adenylate Kinase Complexed with Its Substrates MgATP and AMP by Krishnamurthy, Harini 17
10. Discovering General Properties of Cis Regulatory Elements by Martinez, Carlos 18
11. Modelling Gender Difference in Analysing Genotyping Data by Park, Leeyoung 19
12. Use of Lipid Analysis and Mutagenesis to Optimize Crystallization of Cytochrome c Oxidase from Rhodobacter sphaeroides by Qin, Ling 20
13. Structural Determinants that Mediate CAR/RXR Heterodimerization and Ligand Dependent/Independent Activation by Reynolds, Ross and Xu, Eric 21
14. Molecular Dynamics of Wild-type and R481K Mutant of Rhodobacter sphaeroides Cytochrome c Oxidase: Investigations of Water Chain Formation and Possible Proton Pumping Routes by Seibold, Steve 22
15. FIRST: Determining the Steps in Protein Foldingby Stumpff-Kane, Andrew 23
16. Structure-based Ligand Screening and Design for tRNA Synthetase Inhibitors by Sukuru, Chetan 24
17. Molecular Dynamics Simulations of Membrane Proteins in Implicit Membrane Model by Tanizaki, Seiichiro 25
18. Molecular Dynamics Simulations of Large Scale Motion in an Adenylate Kinase by Vieille, Claire 26
19. Transient Kinetic Modeling of Dihydroneopterin Aldolases from Escherichia coli and Staphylococcus Aureus by Wang, Yi 27
20. Biophysical and Structural Studies of HrpA by Wedemeyer, William 28
21. Molecular Dynamics Simulations of Dihydroneopterin Aldolase by Yao, Lishan 29
22. Transcription Factors IIF and IIS and Nucleoside Triphosphate Substrates as Dynamic Probes of the Human RNA Polymerase II Mechanism by Zhang, Chunfen and Burton, Zachary 30

Participant List